Prognyl (Human Chorionic Gonadotropin) is a prescription medication containing chorionic gonadotropin obtained from a natural origin. Chorionic gonadotropin is a polypeptide hormone normally found in the female body during the early months of pregnancy. It is synthesized in syncytiotrophoblast cells of the placenta, and is responsible for increasing the production of progesterone, a pregnancy-sustaining hormone.

Prognyl (Human Chorionic Gonadotropin) is used by male athletes for its ability to increase endogenous testosterone production, generally during, or at the conclusion of, a steroid cycle, when natural hormone production has been interrupted.

Side effects

Common side effects associated with the administration of Prognyl (Human Chorionic Gonadotropin) include headache, irritability, restlessness, fatigue, depression, swelling, appareance of female breasts in men, pain in the area where you received the injection.

Less common side effects include abdominal or stomach pain, bloating, decreased amount of urine, indigestions, nausea, vomiting, diarrhea, pelvic pain, shortness of breath, weight gain.

General Administration

Prognyl (Human Chorionic Gonadotropin) is generally given by intramuscular injection. Peak concentrations of chorionic gonadotropin occur approximately 6 hours after intramuscular injection, and 16 to 20 hours after subcutaneous injection.

Administration for men

Bodybuilders and athletes use Prognyl (Human Chorionic Gonadotropin) either on cycle, in an effort to maintain testicular integrity during steroid administration, or after a cycle, to help restore hormonal homeostasis more quickly. Both types of use are deemed effective when properly applied.

Post-Cycle

Prognyl (Human Chorionic Gonadotropin) is often used with other medications as part of an in- depth Post Cycle Therapy (PCT) program focused on restoring endogenous testosterone production more rapidly at the end of a steroid cycle. Protocols for the post-cycle use of Prognyl (Human Chorionic Gonadotropin) generally call for the administration of 2000-3000 Units every 2nd or 3rd day, taken for no longer than 2 or 3 weeks.

On-Cycle

Bodybuilders and athletes may also administer Prognyl (Human Chorionic Gonadotropin) throughout a steroid cycle, in an effort to avoid testicular atrophy and the resulting reduced ability to respond to LH stimulus. It is important to remember that the dosage needs to be carefully monitored with this type of use, as high levels of Prognyl (Human Chorionic Gonadotropin) may cause increased testicular aromatase expression (raising estrogen levels), and also desensitize the testes to LH. Current protocols for the use of Prognyl (Human Chorionic Gonadotropin) in this manner involve administering 250 IU subcutaneously every 3rd or 4th day throughout the length of the steroid cycle. Higher doses may be necessary for some individuals, but still no point should exceed 500 IU per injection.

Administration for women

Prognyl (Human Chorionic Gonadotropin) is not used by women for physique- or performance- enhancing purposes.

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